2 papers
physics.bio-ph2024
Applying an electrostatic cross-correlation to the CFTR-ATP interaction
Alex Saad-Falcon, Mark Bolding, James Dee +4
The cystic fibrosis transmembrane conductance regulator (CFTR) is an important membrane protein in vertebrates. The function of CFTR is to transport chloride ions across the cell m…
q-bio.QM2021
A factor graph EM algorithm for inference of kinetic microstates from patch clamp measurements
Alexander S. Moffett, Guiying Cui, Peter J. Thomas +4
We derive a factor graph EM (FGEM) algorithm, a technique that permits combined parameter estimation and statistical inference, to determine hidden kinetic microstates from patch c…