19 citations · 56 across the 27 of their papers we have counts for
28 papers
NuNext: Reframing Nucleus Detection as Next-Point Detection
Zhongyi Shui, Honglin Li, Xiaozhong Ji +7
Nucleus detection in histopathology is pivotal for a wide range of clinical applications. Existing approaches either regress nuclear proxy maps that require complex post-processing…
CPathAgent: An Agent-based Foundation Model for Interpretable High-Resolution Pathology Image Analysis Mimicking Pathologists' Diagnostic Logic
Yuxuan Sun, Yixuan Si, Chenglu Zhu +5
Recent advances in computational pathology have led to the emergence of numerous foundation models. These models typically rely on general-purpose encoders with multi-instance lear…
PathVQ: Reforming Computational Pathology Foundation Model for Whole Slide Image Analysis via Vector Quantization
Honglin Li, Zhongyi Shui, Yunlong Zhang +2
Computational pathology and whole-slide image (WSI) analysis are pivotal in cancer diagnosis and prognosis. However, the ultra-high resolution of WSIs presents significant modeling…
Towards Effective and Efficient Context-aware Nucleus Detection in Histopathology Whole Slide Images
Zhongyi Shui, Honglin Li, Yunlong Zhang +7
Nucleus detection in histopathology whole slide images (WSIs) is crucial for a broad spectrum of clinical applications. The gigapixel size of WSIs necessitates the use of sliding w…
CPath-Omni: A Unified Multimodal Foundation Model for Patch and Whole Slide Image Analysis in Computational Pathology
Yuxuan Sun, Yixuan Si, Chenglu Zhu +7
The emergence of large multimodal models (LMMs) has brought significant advancements to pathology. Previous research has primarily focused on separately training patch-level and wh…
Panther: Illuminate the Sight of Multimodal LLMs with Instruction-Guided Visual Prompts
Honglin Li, Yuting Gao, Chenglu Zhu +3
Multimodal large language models (MLLMs) are closing the gap to human visual perception capability rapidly, while, still lag behind on attending to subtle images details or locatin…
Rethinking Transformer for Long Contextual Histopathology Whole Slide Image Analysis
Honglin Li, Yunlong Zhang, Pingyi Chen +3
Histopathology Whole Slide Image (WSI) analysis serves as the gold standard for clinical cancer diagnosis in the daily routines of doctors. To develop computer-aided diagnosis mode…
Large-scale cervical precancerous screening via AI-assisted cytology whole slide image analysis
Honglin Li, Yusuan Sun, Chenglu Zhu +8
Cervical Cancer continues to be the leading gynecological malignancy, posing a persistent threat to women's health on a global scale. Early screening via cytology Whole Slide Image…
WSI-VQA: Interpreting Whole Slide Images by Generative Visual Question Answering
Pingyi Chen, Chenglu Zhu, Sunyi Zheng +2
Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results…
PathGen-1.6M: 1.6 Million Pathology Image-text Pairs Generation through Multi-agent Collaboration
Yuxuan Sun, Yunlong Zhang, Yixuan Si +7
Vision Language Models (VLMs) like CLIP have attracted substantial attention in pathology, serving as backbones for applications such as zero-shot image classification and Whole Sl…
AEM: Attention Entropy Maximization for Multiple Instance Learning based Whole Slide Image Classification
Yunlong Zhang, Honglin Li, Yunxuan Sun +4
Multiple Instance Learning (MIL) effectively analyzes whole slide images but faces overfitting due to attention over-concentration. While existing solutions rely on complex archite…
PathMMU: A Massive Multimodal Expert-Level Benchmark for Understanding and Reasoning in Pathology
Yuxuan Sun, Hao Wu, Chenglu Zhu +11
The emergence of large multimodal models has unlocked remarkable potential in AI, particularly in pathology. However, the lack of specialized, high-quality benchmark impeded their…
Long-MIL: Scaling Long Contextual Multiple Instance Learning for Histopathology Whole Slide Image Analysis
Honglin Li, Yunlong Zhang, Chenglu Zhu +3
Histopathology image analysis is the golden standard of clinical diagnosis for Cancers. In doctors daily routine and computer-aided diagnosis, the Whole Slide Image (WSI) of histop…
Test-Time Training for Semantic Segmentation with Output Contrastive Loss
Yunlong Zhang, Yuxuan Sun, Sunyi Zheng +3
Although deep learning-based segmentation models have achieved impressive performance on public benchmarks, generalizing well to unseen environments remains a major challenge. To i…
WsiCaption: Multiple Instance Generation of Pathology Reports for Gigapixel Whole-Slide Images
Pingyi Chen, Honglin Li, Chenglu Zhu +3
Whole slide images are the foundation of digital pathology for the diagnosis and treatment of carcinomas. Writing pathology reports is laborious and error-prone for inexperienced p…
Unleashing the Power of Prompt-driven Nucleus Instance Segmentation
Zhongyi Shui, Yunlong Zhang, Kai Yao +7
Nucleus instance segmentation in histology images is crucial for a broad spectrum of clinical applications. Current dominant algorithms rely on regression of nuclear proxy maps. Di…
Attention-Challenging Multiple Instance Learning for Whole Slide Image Classification
Yunlong Zhang, Honglin Li, Yuxuan Sun +3
In the application of Multiple Instance Learning (MIL) methods for Whole Slide Image (WSI) classification, attention mechanisms often focus on a subset of discriminative instances,…
Exploring Unsupervised Cell Recognition with Prior Self-activation Maps
Pingyi Chen, Chenglu Zhu, Zhongyi Shui +4
The success of supervised deep learning models on cell recognition tasks relies on detailed annotations. Many previous works have managed to reduce the dependency on labels. Howeve…
Unleashing the Strengths of Unlabeled Data in Pan-cancer Abdominal Organ Quantification: the FLARE22 Challenge
Jun Ma, Yao Zhang, Song Gu +26
Quantitative organ assessment is an essential step in automated abdominal disease diagnosis and treatment planning. Artificial intelligence (AI) has shown great potential to automa…
Semi-supervised Cell Recognition under Point Supervision
Zhongyi Shui, Yizhi Zhao, Sunyi Zheng +6
Cell recognition is a fundamental task in digital histopathology image analysis. Point-based cell recognition (PCR) methods normally require a vast number of annotations, which is…
PathAsst: A Generative Foundation AI Assistant Towards Artificial General Intelligence of Pathology
Yuxuan Sun, Chenglu Zhu, Sunyi Zheng +6
As advances in large language models (LLMs) and multimodal techniques continue to mature, the development of general-purpose multimodal large language models (MLLMs) has surged, of…
Task-specific Fine-tuning via Variational Information Bottleneck for Weakly-supervised Pathology Whole Slide Image Classification
Honglin Li, Chenglu Zhu, Yunlong Zhang +5
While Multiple Instance Learning (MIL) has shown promising results in digital Pathology Whole Slide Image (WSI) classification, such a paradigm still faces performance and generali…
Unsupervised Dense Nuclei Detection and Segmentation with Prior Self-activation Map For Histology Images
Pingyi Chen, Chenglu Zhu, Zhongyi Shui +4
The success of supervised deep learning models in medical image segmentation relies on detailed annotations. However, labor-intensive manual labeling is costly and inefficient, esp…
End-to-end cell recognition by point annotation
Zhongyi Shui, Shichuan Zhang, Chenglu Zhu +4
Reliable quantitative analysis of immunohistochemical staining images requires accurate and robust cell detection and classification. Recent weakly-supervised methods usually estim…