most citedFluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications

46 citations · 142 across the 6 of their papers we have counts for

collaborators

6 papers

physics.med-ph2024★ 11 cited

Facile One Pot Synthesis of Hybrid Core-Shell Silica-Based Sensors for Live Imaging of Dissolved Oxygen and Hypoxia Mapping in 3D cell models

Helena Iuele, Stefania Forciniti, Valentina Onesto +6

Fluorescence imaging allows for non-invasively visualizing and measuring key physiological parameters like pH and dissolved oxygen. In our work, we created two ratiometric fluoresc…

physics.bio-ph2024★ 10 cited

A Fluorescent Ratiometric Potassium Sensor Based on IPG4-Silica Microparticles for Selective Detection and Fluorescence Imaging of Potassium Cations

Francesco Colella, Stefania Forciniti, Valentina Onesto +4

Potassium cations play many important roles in living organisms, especially in electro-physiology, since they are involved in neurotransmission and muscle contractions. We report t…

physics.bio-ph2024★ 15 cited

Highly Sensitive Ratiometric Fluorescent Fiber Matrixes for Oxygen Sensing with Micrometer-Spatial Resolution

Giuliana Grasso, Valentina Onesto, Stefania Forciniti +8

Oxygen (O2)-sensing matrices are promising tools for the live monitoring of extracellular O2 consumption levels in long-term cell cultures. In this study, ratiometric O2-sensing me…

physics.bio-ph2024★ 33 cited

A pH Sensor Scaffold for Mapping Spatiotemporal Gradients in Three Dimensional In Vitro Tumour Models

Riccardo Rizzo, Valentina Onesto, Stefania Forciniti +6

The detection of extracellular pH at single cell resolution is challenging and requires advanced sensibility. Sensing pH at a high spatial and temporal resolution might provide cru…

physics.app-ph2024★ 46 cited

Fluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications

Giuliana Grasso, Francesco Colella, Stefania Forciniti +7

The tumor microenvironment (TME) features distinct hallmarks, including acidosis, hypoxia, reactive oxygen species (ROS) generation, and altered ion fluxes, which are crucial targe…

physics.chem-ph2021★ 27 cited

Highly sensitive fluorescent pH microsensor based on the ratiometric dye pyranine immobilized on silica microparticles

Anil Chandra, Saumya Prasad, Helena Iuele +5

Pyranine (HPTS) is a remarkably interesting pH sensitive dye that has been used for plenty of applications. Its high quantum yield and extremely sensitive ratiometric fluorescence…