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cs.CE2019★ 19 cited
Bayesian inference based process design and uncertainty analysis of simulated moving bed chromatographic systems
Qiao-Le He, Liming Zhao
Prominent features of simulated moving bed (SMB) chromatography processes in the downstream processing is based on the determination of operating conditions. However, effects of di…
cs.CE2019
Model-based process design of a ternary protein separation using multi-step gradient ion-exchange SMB chromatography
Qiao-Le He, Eric von Lieres, Zhaoxi Sun +1
Model-based process design of ion-exchange simulated moving bed (IEX-SMB) chromatography for center-cut separation of proteins is studied. Use of nonlinear binding models that desc…