4 citations · 6 across the 5 of their papers we have counts for
3 papers · 1 filter
Study of the Parent-of-origin effect in monogenic diseases with variable age of onset. Application on ATTRv
Flora Alarcon, Violaine Planté-Bordeneuve, Gregory Nuel
In genetic diseases with variable age of onset, an accurate estimation of the survival function for the mutation carriers and also modifying factors effects estimations are importa…
Semi-Parametric Survival Estimation for pedigrees
Flora Alarcon, Gregory Nuel, Violaine Plante-Bordeneuve
Mendelian diseases are determined by a single mutation in a given gene. However, in the case of diseases with late onset, the age at onset is variable; it can even be the case that…
Non-subjective power analysis to detect G*E interactions in Genome-Wide Association Studies in presence of confounding factor
Flora Alarcon, Vittorio Perduca, Gregory Nuel
It is generally acknowledged that most complex diseases are affected in part by interactions between genes and genes and/or between genes and environmental factors. Taking into acc…