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SABRE Hyperpolarization of Unmodified Amino Acids in Partially Aqueous Media: L-[1-13C]-Valine as a Model System
Oksana A. Bondar, Thomas B. R. Robertson
Hyperpolarization techniques enhance the sensitivity of nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI), enabling detection of low concentration metabolites a…
Metabolic Reactions Studied by Zero- and Low-Field Nuclear Magnetic Resonance
James Eills, Román Picazo-Frutos, Oksana Bondar +8
State-of-the-art magnetic resonance imaging uses hyperpolarized molecules to track metabolism in vivo, but large superconducting magnets are required, and the strong magnetic field…
Effect of the hydrogenation solvent in the PHIP-SAH hyperpolarization of [1- 13 C]pyruvate
Oksana Bondar, Eleonora Cavallari, Carla Carrera +2
ParaHydrogen Induced Polarization-Side Arm Hydrogenation (PHIP-SAH) is an inexpensive tool to obtain hyperpolarized pyruvate (and other metabolites) that can be applied to in-vivo…