5 papers
PDFBench: A Benchmark for De novo Protein Design from Function
Jiahao Kuang, Nuowei Liu, Jie Wang +3
Function-guided protein design is a crucial task with significant applications in drug discovery and enzyme engineering. However, the field lacks a unified and comprehensive evalua…
DVAGen: Dynamic Vocabulary Augmented Generation
Wei Du, Nuowei Liu, Jie Wang +4
Language models trained with a fixed vocabulary struggle to generalize to novel or out-of-vocabulary words, limiting their flexibility in handling diverse token combinations. Exist…
Protein Design with Dynamic Protein Vocabulary
Nuowei Liu, Jiahao Kuang, Yanting Liu +4
Protein design is a fundamental challenge in biotechnology, aiming to design novel sequences with specific functions within the vast space of possible proteins. Recent advances in…
EvoLlama: Enhancing LLMs' Understanding of Proteins via Multimodal Structure and Sequence Representations
Nuowei Liu, Changzhi Sun, Tao Ji +4
Current Large Language Models (LLMs) for understanding proteins primarily treats amino acid sequences as a text modality. Meanwhile, Protein Language Models (PLMs), such as ESM-2,…
CERD: A Comprehensive Chinese Rhetoric Dataset for Rhetorical Understanding and Generation in Essays
Nuowei Liu, Xinhao Chen, Hongyi Wu +6
Existing rhetorical understanding and generation datasets or corpora primarily focus on single coarse-grained categories or fine-grained categories, neglecting the common interrela…