2 papers
q-bio.BM2024
Multi-variable control to mitigate loads in CRISPRa networks: Extended Version
Krishna Manoj, Theodore W. Grunberg, Domitilla Del Vecchio
The discovery of CRISPR-mediated gene activation (CRISPRa) has transformed the way in which we perform genetic screening, bioproduction and therapeutics through its ability to scal…
cs.ET2021
What Is the Trait d'Union between Retroactivity and Molecular Communication Performance Limits?
Francesca Ratti, Maurizio Magarini, Domitilla Del Vecchio
Information exchange is a critical process in all communication systems, including biological ones. The concept of retroactivity represents the loads that downstream modules apply…