3 papers
q-bio.BM2021
Proteomics Standards Initiatives ProForma 2.0 Unifying the encoding of Proteoforms and Peptidoforms
Richard D. LeDuc, Eric W. Deutsch, Pierre-Alain Binz +15
There is the need to represent in a standard manner all the possible variations of a protein or peptide primary sequence, including both artefactual and post-translational modifica…
q-bio.BM2021
New views of old proteins: clarifying the enigmatic proteome
Participants in a NIH Workshop on Functional, Integrative Proteomics, : +20
All human diseases involve proteins, yet our current tools to characterize and quantify them are limited. To better elucidate proteins across space, time, and molecular composition…
q-bio.TO2021
Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging
John W. Hickey, Elizabeth K. Neumann, Andrea J. Radtke +21
Tissues and organs are composed of distinct cell types that must operate in concert to perform physiological functions. Efforts to create high-dimensional biomarker catalogs of the…