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ContiStain: Cross-Domain Relation-Preserving Distillation for Continual Multi-Domain Virtual IHC Staining
Fuqiang Chen, Yifeng Wang, Hongpeng Wang +1
A unified multiplex virtual staining model enables scalable and non-destructive multiplex analysis from H&E slides while promoting parameter efficiency, shared pathological knowled…
PGVMS: A Prompt-Guided Unified Framework for Virtual Multiplex IHC Staining with Pathological Semantic Learning
Fuqiang Chen, Ranran Zhang, Wanming Hu +6
Immunohistochemical (IHC) staining enables precise molecular profiling of protein expression, with over 200 clinically available antibody-based tests in modern pathology. However,…
A Semantically Enhanced Generative Foundation Model Improves Pathological Image Synthesis
Xianchao Guan, Zhiyuan Fan, Yifeng Wang +11
The development of clinical-grade artificial intelligence in pathology is limited by the scarcity of diverse, high-quality annotated datasets. Generative models offer a potential s…
USIGAN: Unbalanced Self-Information Feature Transport for Weakly Paired Image IHC Virtual Staining
Yue Peng, Bing Xiong, Fuqiang Chen +5
Immunohistochemical (IHC) virtual staining is a task that generates virtual IHC images from H\&E images while maintaining pathological semantic consistency with adjacent slices. Th…