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cond-mat.mtrl-sci2022★ 1 cited
Multi-scale modeling of folic acid-functionalized TiO nanoparticles for active targeting of tumor cells
Edoardo Donadoni, Paulo Siani, Giulia Frigerio +1
Strategies based on the active targeting of tumor cells are emerging as smart and efficient nanomedical procedures. Folic acid (FA) is a vitamin and a well-established tumor target…
cond-mat.soft2022★ 27 cited
Molecular dynamics simulations of cRGD-conjugated PEGylated TiO nanoparticles for targeted photodynamic therapy
Paulo Siani, Giulia Frigerio, Edoardo Donadoni +1
The conjugation of high-affinity cRGD-containing peptides is a promising approach in nanomedicine to efficiently reduce off-targeting effects and enhance the cellular uptake by int…