3 citations · 4 across the 10 of their papers we have counts for
7 papers · 1 filter
ChatGPT in Drug Discovery: A Case Study on Anti-Cocaine Addiction Drug Development with Chatbots
Rui Wang, Hongsong Feng, Guo-Wei Wei
The birth of ChatGPT, a cutting-edge language model-based chatbot developed by OpenAI, ushered in a new era in AI. However, due to potential pitfalls, its role in rigorous scientif…
Artificial intelligence-aided protein engineering: from topological data analysis to deep protein language models
Yuchi Qiu, Guo-Wei Wei
Protein engineering is an emerging field in biotechnology that has the potential to revolutionize various areas, such as antibody design, drug discovery, food security, ecology, an…
Multi-objective Molecular Optimization for Opioid Use Disorder Treatment Using Generative Network Complex
Hongsong Feng, Rui Wang, Chang-Guo Zhan +1
Opioid Use Disorder (OUD) has emerged as a significant global public health issue, with complex multifaceted conditions. Due to the lack of effective treatment options for various…
Persistent Laplacian-enhanced Algorithm for Scarcely Labeled Data Classification
Gokul Bhusal, Ekaterina Merkurjev, Guo-Wei Wei
The success of many machine learning (ML) methods depends crucially on having large amounts of labeled data. However, obtaining enough labeled data can be expensive, time-consuming…
Persistent hyperdigraph homology and persistent hyperdigraph Laplacians
Dong Chen, Jian Liu, Jie Wu +1
Hypergraphs are useful mathematical models for describing complex relationships among members of a structured graph, while hyperdigraphs serve as a generalization that can encode a…
Machine-learning Repurposing of DrugBank Compounds for Opioid Use Disorder
Hongsong Feng, Jian Jiang, Guo-Wei Wei
Opioid use disorder (OUD) is a chronic and relapsing condition that involves the continued and compulsive use of opioids despite harmful consequences. The development of medication…
Machine-learning Analysis of Opioid Use Disorder Informed by MOR, DOR, KOR, NOR and ZOR-Based Interactome Networks
Hongsong Feng, Rana Elladki, Jian Jiang +1
Opioid use disorder (OUD) continuously poses major public health challenges and social implications worldwide with dramatic rise of opioid dependence leading to potential abuse. De…