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Further analysis of metagenomic datasets containing GD and GX pangolin CoVs indicates widespread contamination, undermining pangolin host attribution
Adrian Jones, Steven E. Massey, Daoyu Zhang +2
The only animals other than bats reported to have been infected with SARS-CoV-2-related coronaviruses (SARS2r-CoVs) prior to the COVID-19 pandemic are pangolins. In early 2020 mult…
Laotian Bat Sarbecovirus BANAL-236 Uses ACE2 to Infect Cells by an Unknown Mechanism
Steven Carl Quay
A manuscript identified bat sarbecoviruses with high sequence homology to SARS-CoV-2 found in caves in Laos that can directly infect human cells via the human ACE2 receptor (Corona…
Nipah virus vector sequences in COVID-19 patient samples sequenced by the Wuhan Institute of Virology
Steven C. Quay, Daoyu Zhang, Adrian Jones +1
We report the detection of Nipah virus in an infectious clone format, a BSL4-level pathogen and CDC-designated Bioterrorism Agent, in raw RNA-Seq sequencing reads deposited by the…
Analysis of pangolin metagenomic datasets reveals significant contamination, raising concerns for pangolin CoV host attribution
Adrian Jones, Daoyu Zhang, Yuri Deigin +1
Metagenomic datasets from pangolin tissue specimens have previously yielded SARS-related coronaviruses which show high homology in their receptor binding domain to SARS-CoV-2, sugg…