activity
20142021
most citedParameter-free methods distinguish Wnt pathway models and guide design of experiments

50 citations · 65 across the 3 of their papers we have counts for

collaborators

5 papers

q-bio.QM2021

Julia for Biologists

Elisabeth Roesch, Joe G. Greener, Adam L. MacLean +4

Increasing emphasis on data and quantitative methods in the biomedical sciences is making biological research more computational. Collecting, curating, processing, and analysing la…

q-bio.QM2021★ 2 cited

Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through Analysis of Viral Genomics and Structure

Halie M. Rando, Adam L. MacLean, Alexandra J. Lee +31

The novel coronavirus SARS-CoV-2, which emerged in late 2019, has since spread around the world and infected hundreds of millions of people with coronavirus disease 2019 (COVID-19)…

math.DS2015★ 13 cited

Conditional Random Matrix Ensembles and the Stability of Dynamical Systems

Paul Kirk, Delphine M. Y. Rolando, Adam L. MacLean +1

There has been a long-standing and at times fractious debate whether complex and large systems can be stable. In ecology, the so-called `diversity-stability debate' arose because m…

q-bio.QM2015

Mathematical and Statistical Techniques for Systems Medicine: The Wnt Signaling Pathway as a Case Study

Adam L. MacLean, Heather A. Harrington, Michael P. H. Stumpf +1

The last decade has seen an explosion in models that describe phenomena in systems medicine. Such models are especially useful for studying signaling pathways, such as the Wnt path…

q-bio.QM2014★ 50 cited

Parameter-free methods distinguish Wnt pathway models and guide design of experiments

Adam L. MacLean, Zvi Rosen, Helen M. Byrne +1

The canonical Wnt signaling pathway, mediated by -catenin, is crucially involved in development, adult stem cell tissue maintenance and a host of diseases including cancer. We u…