activity
20212025
most citedMitosis domain generalization in histopathology images -- The MIDOG challenge

162 citations · 166 across the 8 of their papers we have counts for

collaborators

10 papers

eess.IV2025

Sequential Hard Mining: a data-centric approach for Mitosis Detection

Maxime W. Lafarge, Viktor H. Koelzer

With a continuously growing availability of annotated datasets of mitotic figures in histology images, finding the best way to optimally use with this unprecedented amount of data…

cs.CV2025

Tera-MIND: Tera-scale mouse brain simulation via spatial mRNA-guided diffusion

Jiqing Wu, Ingrid Berg, Yawei Li +2

Holistic 3D modeling of molecularly defined brain structures is crucial for understanding complex brain functions. Using emerging tissue profiling technologies, researchers charted…

eess.IV2023

SoftCTM: Cell detection by soft instance segmentation and consideration of cell-tissue interaction

Lydia A. Schoenpflug, Viktor H. Koelzer

Detecting and classifying cells in histopathology H\&E stained whole-slide images is a core task in computational pathology, as it provides valuable insight into the tumor microenv…

cs.CV2023★ 2 cited

Domain generalization across tumor types, laboratories, and species -- insights from the 2022 edition of the Mitosis Domain Generalization Challenge

Marc Aubreville, Nikolas Stathonikos, Taryn A. Donovan +27

Recognition of mitotic figures in histologic tumor specimens is highly relevant to patient outcome assessment. This task is challenging for algorithms and human experts alike, with…

cs.LG2023★ 1 cited

CohortFinder: an open-source tool for data-driven partitioning of biomedical image cohorts to yield robust machine learning models

Fan Fan, Georgia Martinez, Thomas Desilvio +10

Batch effects (BEs) refer to systematic technical differences in data collection unrelated to biological variations whose noise is shown to negatively impact machine learning (ML)…

eess.IV2023

Multi-task learning for tissue segmentation and tumor detection in colorectal cancer histology slides

Lydia A. Schoenpflug, Maxime W. Lafarge, Anja L. Frei +1

Automating tissue segmentation and tumor detection in histopathology images of colorectal cancer (CRC) is an enabler for faster diagnostic pathology workflows. At the same time it…

eess.IV2023

Fine-Grained Hard Negative Mining: Generalizing Mitosis Detection with a Fifth of the MIDOG 2022 Dataset

Maxime W. Lafarge, Viktor H. Koelzer

Making histopathology image classifiers robust to a wide range of real-world variability is a challenging task. Here, we describe a candidate deep learning solution for the Mitosis…

eess.IV2022★ 162 cited

Mitosis domain generalization in histopathology images -- The MIDOG challenge

Marc Aubreville, Nikolas Stathonikos, Christof A. Bertram +32

The density of mitotic figures within tumor tissue is known to be highly correlated with tumor proliferation and thus is an important marker in tumor grading. Recognition of mitoti…

cs.LG2022★ 1 cited

Towards IID representation learning and its application on biomedical data

Jiqing Wu, Inti Zlobec, Maxime Lafarge +2

Due to the heterogeneity of real-world data, the widely accepted independent and identically distributed (IID) assumption has been criticized in recent studies on causality. In thi…

cs.CV2021

Rotation Invariance and Extensive Data Augmentation: a strategy for the Mitosis Domain Generalization (MIDOG) Challenge

Maxime W. Lafarge, Viktor H. Koelzer

Automated detection of mitotic figures in histopathology images is a challenging task: here, we present the different steps that describe the strategy we applied to participate in…