16 citations · 19 across the 9 of their papers we have counts for
3 papers · 1 filter
Weak instruments in multivariable Mendelian randomization: methods and practice
Ashish Patel, James Lane, Stephen Burgess
The method of multivariable Mendelian randomization uses genetic variants to instrument multiple exposures, to estimate the effect that a given exposure has on an outcome condition…
Estimating time-varying exposure effects through continuous-time modelling in Mendelian randomization
Haodong Tian, Ashish Patel, Stephen Burgess
Mendelian randomization is an instrumental variable method that utilizes genetic information to investigate the causal effect of a modifiable exposure on an outcome. In most cases,…
A frequentist test of proportional colocalization after selecting relevant genetic variants
Ashish Patel, John C. Whittaker, Stephen Burgess
Colocalization analyses assess whether two traits are affected by the same or distinct causal genetic variants in a single gene region. A class of Bayesian colocalization tests are…