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stat.ME2026
Multivariable Mendelian randomization with weak instruments: a comparison of Bayesian and frequentist methods
Andrew J. Grant, Ashish Patel, Stephen Burgess
Weak instruments are a well known limitation for valid causal inference in Mendelian randomization studies. In the single exposure setting, weak instrument bias can be mitigated by…
stat.ME2026
Efficient semiparametric estimation of marginal treatment effects with genetic instrumental variables
Ashish Patel, Francis J DiTraglia, Stephen Burgess
Alcohol misuse is a key target of public health strategies aimed at reducing cardiovascular risk. The effect of excessive alcohol consumption on blood pressure may vary systematica…