2 papers
q-bio.GN2024
Absorb & Escape: Overcoming Single Model Limitations in Generating Genomic Sequences
Zehui Li, Yuhao Ni, Guoxuan Xia +4
Abstract Recent advances in immunology and synthetic biology have accelerated the development of deep generative methods for DNA sequence design. Two dominant approaches in this fi…
q-bio.GN2024
DiscDiff: Latent Diffusion Model for DNA Sequence Generation
Zehui Li, Yuhao Ni, William A V Beardall +4
This paper introduces a novel framework for DNA sequence generation, comprising two key components: DiscDiff, a Latent Diffusion Model (LDM) tailored for generating discrete DNA se…