148 citations · 315 across the 14 of their papers we have counts for
14 papers
Toward Global Large Language Models in Medicine
Rui Yang, Huitao Li, Weihao Xuan +47
Despite continuous advances in medical technology, the global distribution of health care resources remains uneven. The development of large language models (LLMs) has transformed…
RELEAP: Reinforcement-Enhanced Label-Efficient Active Phenotyping for Electronic Health Records
Yang Yang, Kathryn I. Pollak, Bibhas Chakraborty +3
Objective: Electronic health record (EHR) phenotyping often relies on noisy proxy labels, which undermine the reliability of downstream risk prediction. Active learning can reduce…
Fairness-Aware Interpretable Modeling (FAIM) for Trustworthy Machine Learning in Healthcare
Mingxuan Liu, Yilin Ning, Yuhe Ke +5
The escalating integration of machine learning in high-stakes fields such as healthcare raises substantial concerns about model fairness. We propose an interpretable framework - Fa…
Developing Federated Time-to-Event Scores Using Heterogeneous Real-World Survival Data
Siqi Li, Yuqing Shang, Ziwen Wang +7
Survival analysis serves as a fundamental component in numerous healthcare applications, where the determination of the time to specific events (such as the onset of a certain dise…
Optimal Adaptive SMART Designs with Binary Outcomes
Rik Ghosh, Bibhas Chakraborty, Inbal Nahum-Shani +2
In a sequential multiple-assignment randomized trial (SMART), a sequence of treatments is given to a patient over multiple stages. In each stage, randomization may be done to alloc…
Federated and distributed learning applications for electronic health records and structured medical data: A scoping review
Siqi Li, Pinyan Liu, Gustavo G. Nascimento +12
Federated learning (FL) has gained popularity in clinical research in recent years to facilitate privacy-preserving collaboration. Structured data, one of the most prevalent forms…
FedScore: A privacy-preserving framework for federated scoring system development
Siqi Li, Yilin Ning, Marcus Eng Hock Ong +8
We propose FedScore, a privacy-preserving federated learning framework for scoring system generation across multiple sites to facilitate cross-institutional collaborations. The Fed…
Handling missing values in healthcare data: A systematic review of deep learning-based imputation techniques
Mingxuan Liu, Siqi Li, Han Yuan +7
Objective: The proper handling of missing values is critical to delivering reliable estimates and decisions, especially in high-stakes fields such as clinical research. The increas…
AutoScore-Ordinal: An interpretable machine learning framework for generating scoring models for ordinal outcomes
Seyed Ehsan Saffari, Yilin Ning, Xie Feng +5
Background: Risk prediction models are useful tools in clinical decision-making which help with risk stratification and resource allocations and may lead to a better health care fo…
A novel interpretable machine learning system to generate clinical risk scores: An application for predicting early mortality or unplanned readmission in a retrospective cohort study
Yilin Ning, Siqi Li, Marcus Eng Hock Ong +4
Risk scores are widely used for clinical decision making and commonly generated from logistic regression models. Machine-learning-based methods may work well for identifying import…
Benchmarking emergency department triage prediction models with machine learning and large public electronic health records
Feng Xie, Jun Zhou, Jin Wee Lee +10
The demand for emergency department (ED) services is increasing across the globe, particularly during the current COVID-19 pandemic. Clinical triage and risk assessment have become…
Shapley variable importance clouds for interpretable machine learning
Yilin Ning, Marcus Eng Hock Ong, Bibhas Chakraborty +4
Interpretable machine learning has been focusing on explaining final models that optimize performance. The current state-of-the-art is the Shapley additive explanations (SHAP) that…
A Penalized Shared-parameter Algorithm for Estimating Optimal Dynamic Treatment Regimens
Palash Ghosh, Xinru Wang, Trikay Nalamada +3
A dynamic treatment regimen (DTR) is a set of decision rules to personalize treatments for an individual using their medical history. The Q-learning-based Q-shared algorithm has be…
Sample size estimation for comparing dynamic treatment regimens in a SMART: a Monte Carlo-based approach and case study with longitudinal overdispersed count outcomes
Jamie Yap, John J. Dziak, Raju Maiti +4
Dynamic treatment regimens (DTRs), also known as treatment algorithms or adaptive interventions, play an increasingly important role in many health domains. DTRs are motivated to a…