activity
20132023
most citedLarge-scale generation of computational models from biochemical pathway maps

185 citations · 261 across the 5 of their papers we have counts for

collaborators

6 papers

q-bio.MN2023★ 6 cited

Reproducibility and FAIR Principles: The Case of a Segment Polarity Network Model

Pedro Mendes

The issue of reproducibility of computational models and the related FAIR principles (findable, accessible, interoperable, and reusable) are examined in a specific test case. I ana…

q-bio.MN2021

ShinyCOPASI: a web-based exploratory interface for COPASI models

Abhishekh Gupta, Pedro Mendes

COPASI is a popular application for simulation and analysis of biochemical networks and their dynamics. While this software is widely used, it works as a standalone application and…

q-bio.OT2018★ 22 cited

Reproducible research using biomodels

Pedro Mendes

Like other types of computational research, modeling and simulation of biological processes (biomodels) is still largely communicated without sufficient detail to allow independent…

q-bio.QM2014

BioPreDyn-bench: benchmark problems for kinetic modelling in systems biology

Alejandro F Villaverde, David Henriques, Kieran Smallbone +10

Dynamic modelling is one of the cornerstones of systems biology. Many research efforts are currently being invested in the development and exploitation of large-scale kinetic model…

q-bio.MN2013★ 48 cited

A Computational Model of Liver Iron Metabolism

Simon Mitchell, Pedro Mendes

Iron is essential for all known life due to its redox properties, however these same properties can also lead to its toxicity in overload through the production of reactive oxygen…

q-bio.MN2013★ 185 cited

Large-scale generation of computational models from biochemical pathway maps

Finja Büchel, Nicolas Rodriguez, Neil Swainston +23

Background: Systems biology projects and omics technologies have led to a growing number of biochemical pathway reconstructions. However, mathematical models are still most often c…