7 citations · 21 across the 10 of their papers we have counts for
10 papers
Fairboard: a quantitative framework for equity assessment of healthcare models
James K. Ruffle, Samia Mohinta, Chris Foulon +5
Despite there now being more than 1,000 FDA-authorised AI medical devices, formal equity assessments -- whether model performance is uniform across patient subgroups -- are rare. H…
Predicting brain tumour enhancement from non-contrast MR imaging with artificial intelligence: a multi-cohort retrospective diagnostic accuracy study
James K Ruffle, Samia Mohinta, Guilherme Pombo +13
Brain tumour MRI typically requires both pre- and post-contrast imaging, but gadolinium is not always desirable (frequent follow-up, renal impairment, allergy, paediatric patients)…
Generalizable automated ischaemic stroke lesion segmentation with vision transformers
Chris Foulon, Robert Gray, James K. Ruffle +13
Ischaemic stroke, a leading cause of death and disability, critically relies on neuroimaging for characterising the anatomical pattern of injury. Diffusion-weighted imaging (DWI) p…
VASARI-auto: equitable, efficient, and economical featurisation of glioma MRI
James K Ruffle, Samia Mohinta, Kelly Pegoretti Baruteau +5
The VASARI MRI feature set is a quantitative system designed to standardise glioma imaging descriptions. Though effective, deriving VASARI is time-consuming and seldom used in clin…
Compressed representation of brain genetic transcription
James K Ruffle, Henry Watkins, Robert J Gray +3
The architecture of the brain is too complex to be intuitively surveyable without the use of compressed representations that project its variation into a compact, navigable space.…
Computational limits to the legibility of the imaged human brain
James K Ruffle, Robert J Gray, Samia Mohinta +5
Our knowledge of the organisation of the human brain at the population-level is yet to translate into power to predict functional differences at the individual-level, limiting clin…
The minimal computational substrate of fluid intelligence
Amy PK Nelson, Joe Mole, Guilherme Pombo +6
The quantification of cognitive powers rests on identifying a behavioural task that depends on them. Such dependence cannot be assured, for the powers a task invokes cannot be expe…
Individualized prescriptive inference in ischaemic stroke
Dominic Giles, Chris Foulon, Guilherme Pombo +8
The gold standard in the treatment of ischaemic stroke is set by evidence from randomized controlled trials, based on simple descriptions of presumptively homogeneous populations.…
Focal and Connectomic Mapping of Transiently Disrupted Brain Function
Michael S. Elmalem, Hanna Moody, James K. Ruffle +5
The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder tas…
Deep forecasting of translational impact in medical research
Amy PK Nelson, Robert J Gray, James K Ruffle +10
The value of biomedical research--a $1.7 trillion annual investment--is ultimately determined by its downstream, real-world impact. Current objective predictors of impact rest on p…