4 papers
Learning Adaptive Perturbation-Conditioned Contexts for Robust Transcriptional Response Prediction
Yinhua Piao, Hyomin Kim, Seonghwan Kim +7
Predicting high-dimensional transcriptional responses to genetic perturbations is challenging because signals are sparse and experimental noise is severe. Existing methods often su…
DNACHUNKER: Learnable Tokenization for DNA Language Models
Taewon Kim, Jihwan Shin, Hyomin Kim +5
DNA language models are increasingly used to represent genomic sequence, yet their effectiveness depends critically on how raw nucleotides are converted into model inputs. Unlike n…
Progressive Multi-Agent Reasoning for Biological Perturbation Prediction
Hyomin Kim, Sang-Yeon Hwang, Jaechang Lim +6
Predicting gene regulation responses to biological perturbations requires reasoning about underlying biological causalities. While large language models (LLMs) show promise for suc…
MT-Mol:Multi Agent System with Tool-based Reasoning for Molecular Optimization
Hyomin Kim, Yunhui Jang, Sungsoo Ahn
Large language models (LLMs) have large potential for molecular optimization, as they can gather external chemistry tools and enable collaborative interactions to iteratively refin…