8 papers
Protocol for an Observational Study on the Effects of Adolescent Physical Activity and Sports Participation on Flourishing and Academic Engagement
William Bekerman, Rebecca E. Hasson, Leah E. Robinson +1
The wide-ranging benefits of physical activity and sports participation among children and adolescents have been closely examined and are reported to include improvements in physic…
Powerful Multivariate Sensitivity Analysis via Sample Splitting in an Observational Study of the Effects of Poverty on Cardiovascular Disease Risk Factors
William Bekerman, Anurag Mehta, Rebecca E. Hasson +3
When assessing the causal effect of an exposure on two or more outcomes in an observational study, a linear combination of outcomes may lessen the sensitivity of a test of the glob…
Beyond the ACE Score: Replicable Combinations of Adverse Childhood Experiences That Worsen Depression Risk
Ruizhe Zhang, Jooyoung Kong, Dylan S. Small +1
Adverse childhood experiences (ACEs) are categories of childhood abuse, neglect, and household dysfunction. Screening by a single additive ACE score (e.g., a cutoff) has po…
Protocol For An Observational Study On The Effects Of Combinations Of Adverse Childhood Experiences On Adult Depression
Ruizhe Zhang, Jooyoung Kong, Dylan S. Small +1
Adverse childhood experiences (ACEs) have been linked to a wide range of negative health outcomes in adulthood. However, few studies have investigated what specific combinations of…
Protocol for an Observational Study on the Effects of Paternal Alcohol Use Disorder on Children's Later Life Outcomes
William Bekerman, Marina Bogomolov, Ruth Heller +4
The harmful effects of growing up with a parent with an alcohol use disorder have been closely examined in children and adolescents, and are reported to include mental and physical…
Planning for gold: Hypothesis screening with split samples for valid powerful testing in matched observational studies
William Bekerman, Abhinandan Dalal, Carlo del Ninno +1
Observational studies are valuable tools for inferring causal effects in the absence of controlled experiments. However, these studies may be biased due to the presence of some rel…
Comparison of CYGNSS and Jason-3 Wind Speed Measurements via Gaussian Processes
William Bekerman, Joseph Guinness
Wind is a critical component of the Earth system and has unmistakable impacts on everyday life. The CYGNSS satellite mission improves observational coverage of ocean winds via a fl…
RZiMM-scRNA: A regularized zero-inflated mixture model framework for single-cell RNA-seq data
Xinlei Mi, William Bekerman, Peter A. Sims +2
Applications of single-cell RNA sequencing in various biomedical research areas have been blooming. This new technology provides unprecedented opportunities to study disease hetero…