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cs.LG2025
SPID: Distilled Protein Backbone Generation
Liyang Xie, Haoran Zhang, Zhendong Wang +2
Diffusion- and flow-based generative models have recently demonstrated strong performance in protein backbone generation tasks, offering unprecedented capabilities for de novo prot…
cs.LG2025
Controllable diffusion-based generation for multi-channel biological data
Haoran Zhang, Mingyuan Zhou, Wesley Tansey
Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial…
cs.LG2021★ 1 cited
CARMS: Categorical-Antithetic-REINFORCE Multi-Sample Gradient Estimator
Alek Dimitriev, Mingyuan Zhou
Accurately backpropagating the gradient through categorical variables is a challenging task that arises in various domains, such as training discrete latent variable models. To thi…