34 papers
Targeted Data Fusion for Region-Specific Survival Effects in the AMP HIV Prevention Trials
Yi Liu, Alexander W. Levis, Ke Zhu +3
The Antibody Mediated Prevention (AMP) trials opened a new scientific frontier by showing that passively administered monoclonal broadly neutralizing antibodies (bnAbs) could preve…
Robust Estimation and Inference with Selective Borrowing in Hybrid Controlled Trials: A Tutorial with SelectiveIntegrative and intFRT
Ke Zhu, Hairong Huang, Shu Yang +1
Hybrid controlled trials (HCTs) augment randomized controlled trials (RCTs) with external controls (ECs) to improve statistical efficiency when RCTs face limited sample sizes, slow…
Bayesian Structured Mediation Analysis With Unobserved Confounders
Yuliang Xu, Shu Yang, Jian Kang
We explore methods to reduce the impact of unobserved confounders on the causal mediation analysis of high-dimensional mediators with spatially smooth structures, such as brain ima…
Spatial causal inference in the presence of preferential sampling to study the impacts of marine protected areas
Dongjae Son, Brian J. Reich, Erin M. Schliep +2
Marine Protected Areas (MPAs) have been established globally to conserve marine resources. Given their maintenance costs and impact on commercial fishing, it is critical to evaluat…
History-Aware Conformal Prediction Sets for Censored Time-to-Event Outcomes
Yuyao Wang, Alexander W. Levis, Shu Yang +1
Existing conformal prediction methods for time-to-event outcomes leverage only baseline covariates, producing prediction intervals that are insufficiently informative to facilitate…
Externally Controlled Trials: A Review of Design and Borrowing Through a Causal Lens
Ke Zhu, Rima Izem, Peng Yang +8
Externally controlled trials (ECTs) are increasingly used when randomized controls are infeasible, unethical, or insufficient, including applications in rare diseases, oncology, pe…