5 papers
Repeated sampling of different individuals within the same clusters to improve precision of longitudinal estimators: the DISC design
Jordan Downey, Avi Kenny
Background: Longitudinal studies often involve repeated cluster sampling of a population at multiple time points, such as in difference-in-differences (DID) studies. Although cohor…
Robust and Efficient Semiparametric Inference for the Stepped Wedge Design
Fan Xia, K. C. Gary Chan, Emily Voldal +3
Stepped wedge designs (SWDs) are increasingly used to evaluate longitudinal cluster-level interventions but pose substantial challenges for valid inference. Because crossover times…
A Review of Methods and Practices for Missing Data in Sequential Multiple Assignment Randomized Trials (SMARTs): An Ancillary Study of a Scoping Review
Nikki L. B. Freeman, Chenyao Yu, Margaret Hoch +5
Background: Missing data poses an acute threat to sequential multiple assignment randomized trial (SMART) analyses because of the sequential treatment structure and response-depend…
Factors affecting power in stepped wedge trials when the treatment effect varies with time
Avi Kenny, Emily C. Voldal, Fan Xia +3
Stepped wedge cluster randomized trials (SW-CRTs) have historically been analyzed using immediate treatment (IT) models, which assume the effect of the treatment is immediate after…
Analysis of Stepped-Wedge Cluster Randomized Trials when treatment effects vary by exposure time or calendar time
Kenneth M. Lee, Elizabeth L. Turner, Avi Kenny
Stepped-wedge cluster randomized trials (SW-CRTs) are traditionally analyzed with models that assume an immediate and sustained treatment effect. Previous work has shown that makin…