Deciphering SCN2A: A comprehensive review of rodent models of Scn2a dysfunction

Katelin E. J Scott, Maria F. Hermosillo Arrieta, Aislinn J. Williams

SCN2A encodes the alpha subunit of the voltage-gated sodium channel Nav1.2, which is involved in action potential initiation and backpropagation in glutamatergic neurons. Mutations…