3 papers
stat.AP2025
Nonparametric estimation of an optimal treatment rule with fused randomized trials and missing effect modifiers
Nicholas Williams, Kara Rudolph, Iván Díaz
A fundamental principle of clinical medicine is that a treatment should only be administered to those patients who would benefit from it. Treatment strategies that assign treatment…
stat.AP2024
Associations between pain-management treatments and opioid use disorder risk among Medicaid patients
Kara E. Rudolph, Nicholas T. Williams, Ivan Diaz +7
Introduction: Chronic pain patients are at increased risk of opioid-misuse. Less is known about the unique risk conferred by each pain-management treatment, as treatments are typic…
stat.ME2024
Two-Step Targeted Minimum-Loss Based Estimation for Non-Negative Two-Part Outcomes
Nicholas T. Williams, Richard Liu, Katherine L. Hoffman +3
Non-negative two-part outcomes are defined as outcomes with a density function that have a zero point mass but are otherwise positive. Examples, such as healthcare expenditure and…