32 citations · 51 across the 5 of their papers we have counts for
6 papers
NANOG assembles into self-limiting aging micelles that drive a sol-gel transition and modulate DNA dynamics
Amandine Hong-Minh, Yair Augusto Gutierrez Fosado, Abbie Guild +4
Proteins and nucleic acids form non-Newtonian liquids with complex rheological properties that contribute to their function in vivo. Here we investigate the rheology of the transcr…
Binding Kinetics Oppositely Regulates type II Topoisomerase Relaxation and Decatenation Activities
Cleis Battaglia, Filippo Conforto, Yair Augusto Gutierrez Fosado +4
Type II Topoisomerases (topo II) are critical to simplify genome topology during transcription and replication. They identify topological problems and resolve them by passing a dou…
Link to Densify: Topological Transitions and Origin of Hysteresis During the (De)Compression of Amorphous Ices
Yair Augusto Gutiérrez Fosado, Davide Michieletto, Fausto Martelli
In this Letter we study the phase transition between amorphous ices and the nature of the hysteresis cycle separating them. We discover that a topological transition takes place as…
Fluidification of Entangled Polymers by Loop Extrusion
Filippo Conforto, Yair Augusto Gutierrez Fosado, Davide Michieletto
Loop extrusion is one of the main processes shaping chromosome organisation across the cell cycle, yet its role in regulating DNA entanglement and nucleoplasm viscoelasticity remai…
Topological Linking Determines Elasticity in Limited Valence Networks
Giorgia Palombo, Simon Weir, Davide Michieletto +1
Understanding the relationship between the microscopic structure and topology of a material and its macroscopic properties is a fundamental challenge across a wide range of systems…
Coarse-Grained Simulation of DNA using LAMMPS
Oliver Henrich, Yair Augusto Gutierrez-Fosado, Tine Curk +1
During the last decade coarse-grained nucleotide models have emerged that allow us to DNA and RNA on unprecedented time and length scales. Among them is oxDNA, a coarse-grained, se…