108 citations · 206 across the 5 of their papers we have counts for
5 papers
Current and future directions in network biology
Marinka Zitnik, Michelle M. Li, Aydin Wells +34
Network biology is an interdisciplinary field bridging computational and biological sciences that has proved pivotal in advancing the understanding of cellular functions and diseas…
The Clinical Trials Puzzle: How Network Effects Limit Drug Discovery
Kishore Vasan, Deisy Gysi, Albert-Laszlo Barabasi
The depth of knowledge offered by post-genomic medicine has carried the promise of new drugs, and cures for multiple diseases. To explore the degree to which this capability has ma…
AI-Bind: Improving Binding Predictions for Novel Protein Targets and Ligands
Ayan Chatterjee, Robin Walters, Zohair Shafi +7
Identifying novel drug-target interactions (DTI) is a critical and rate limiting step in drug discovery. While deep learning models have been proposed to accelerate the identificat…
Comparing multiple networks using the Co-expression Differential Network Analysis (CoDiNA)
Deisy Morselli Gysi, Tiago Miranda Fragoso, Volker Buskamp +2
Biomedical sciences are increasingly recognising the relevance of gene co-expression-networks for analysing complex-systems, phenotypes or diseases. When the goal is investigating…
wTO: an R package for computing weighted topological overlap and consensus networks with an integrated visualization tool
Deisy Morselli Gysi, Andre Voigt, Tiago de Miranda Fragoso +2
Network analyses, such as of gene co-expression networks, metabolic networks and ecological networks have become a central approach for the systems-level study of biological data.…