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q-bio.BM2021
Native state of natural proteins optimises local entropy
Matteo Negri, Guido Tiana, Riccardo Zecchina
The differing ability of polypeptide conformations to act as the native state of proteins has long been rationalized in terms of differing kinetic accessibility or thermodynamic st…
q-bio.BM2018
Spontaneous domain formation in disordered copolymers as a mechanism for chromosome structuring
Matteo Negri, Marco Gherardi, Guido Tiana +1
Motivated by the problem of domain formation in chromosomes, we studied a co--polymer model where only a subset of the monomers feel attractive interactions. These monomers are dis…