most citedReconstruction of the evolutionary history of gene gains and losses since the last universal common ancestor

9 citations · 15 across the 5 of their papers we have counts for

collaborators

5 papers

q-bio.QM2018★ 4 cited

TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations

Haiming Tang, Robert D Finn, Paul D Thomas

Summary: TreeGrafter is a new software tool for annotating protein sequences using annotated phylogenetic trees. Cur-rently, the tool provides annotations to Gene Ontology terms, a…

q-bio.QM2018

Automation of gene function prediction through modeling human curators' decisions in GO phylogenetic annotation project

Haiming Tang, Paul D Thomas, Huaiyu Mi

The Gene Ontology Consortium launched the GO-PAINT project (Phylogenetic Annotation and INference Tool) 9 years ago and is currently being used in the GO Reference Genome Annotatio…

q-bio.PE2018★ 9 cited

Reconstruction of the evolutionary history of gene gains and losses since the last universal common ancestor

Haiming Tang, Paul Thomas, Haoran Xia

Gene gains and losses have shaped the gene repertoire of species since the universal last common ancestor to species today. Genes in extant species were gained at different histori…

q-bio.PE2018★ 1 cited

GOTaxon: Representing the evolution of biological functions in the Gene Ontology

Haiming Tang, Christopher J Mungall, Huaiyu Mi +1

The Gene Ontology aims to define the universe of functions known for gene products, at the molecular, cellular and organism levels. While the ontology is designed to cover all aspe…

q-bio.PE2018★ 1 cited

Inference of gene loss rates after whole genome duplications at early vertebrates through ancient genome reconstructions

Haiming Tang, Angela Wilkins

The famous 2R hypothesis was first proposed by Susumu Ohno in 1970. It states that the two whole genome duplications had shaped the genome of early vertebrates. The most convincing…