activity
20152024
most citedEstimation of extended mixed models using latent classes and latent processes: the R package lcmm

1.1k citations · 1.1k across the 6 of their papers we have counts for

collaborators

7 papers

stat.ME2024

Dynamic prediction of an event using multiple longitudinal markers: a model averaging approach

Reza Hashemi, Taban Baghfalaki, Viviane Philipps +1

Dynamic event prediction, using joint modeling of survival time and longitudinal variables, is extremely useful in personalized medicine. However, the estimation of joint models in…

stat.AP2022★ 24 cited

Describing complex disease progression using joint latent class models for multivariate longitudinal markers and clinical endpoints

Cécile Proust-Lima, Tiphaine Saulnier, Viviane Philipps +5

Neurodegenerative diseases are characterized by numerous markers of progression and clinical endpoints. For instance, Multiple System Atrophy (MSA), a rare neurodegenerative synucl…

stat.ME2021

Joint models for the longitudinal analysis of measurement scales in the presence of informative dropout

Tiphaine Saulnier, Viviane Philipps, Wassilios G Meissner +4

In health cohort studies, repeated measures of markers are often used to describe the natural history of a disease. Joint models allow to study their evolution by taking into accou…

stat.ME2021★ 18 cited

Modeling repeated self-reported outcome data: a continuous-time longitudinal Item Response Theory model

Cécile Proust-Lima, Viviane Philipps, Bastien Perrot +2

Item Response Theory (IRT) models have received growing interest in health science for analyzing latent constructs such as depression, anxiety, quality of life, or cognitive functi…

stat.CO2020★ 1 cited

Robust and Efficient Optimization Using a Marquardt-Levenberg Algorithm with R Package marqLevAlg

Viviane Philipps, Boris P Hejblum, Mélanie Prague +2

Implementations in R of classical general-purpose algorithms for local optimization generally have two major limitations which cause difficulties in applications to complex problem…

stat.ME2018★ 8 cited

A joint model for multiple dynamic processes and clinical endpoints: application to Alzheimer's disease

Cécile Proust-Lima, Viviane Philipps, Jean-François Dartigues

As other neurodegenerative diseases, Alzheimer's disease, the most frequent dementia in the elderly, is characterized by multiple progressive impairments in the brain structure and…

stat.CO2015★ 1.1k cited

Estimation of extended mixed models using latent classes and latent processes: the R package lcmm

Cécile Proust-Lima, Viviane Philipps, Benoit Liquet

The R package lcmm provides a series of functions to estimate statistical models based on linear mixed model theory. It includes the estimation of mixed models and latent class mix…