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q-bio.PE2018
Calculating normal tissue complication probabilities and probabilities of complication-free tumour control from stochastic models of population dynamics
Peter G. Hufton, Elizabeth Buckingham-Jeffery, Tobias Galla
We use a stochastic birth-death model for a population of cells to estimate the normal tissue complication probability (NTCP) under a particular radiotherapy protocol. We specifica…
q-bio.PE2017
Phenotypic switching of populations of cells in a stochastic environment
Peter G. Hufton, Yen Ting Lin, Tobias Galla
In biology phenotypic switching is a common bet-hedging strategy in the face of uncertain environmental conditions. Existing mathematical models often focus on periodically changin…