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stat.AP2018★ 1 cited
Bayesian estimation of a semiparametric recurrent event model with applications to the penetrance estimation of multiple primary cancers in Li-Fraumeni Syndrome
Seung Jun Shin, Jialu Li, Jing Ning +3
A common phenomenon in cancer syndromes is for an individual to have multiple primary cancers at different sites during his/her lifetime. Patients with Li-Fraumeni syndrome (LFS),…
stat.AP2017★ 3 cited
Bayesian Semiparametric Estimation of Cancer-specific Age-at-onset Penetrance with Application to Li-Fraumeni Syndrome
Seung Jun Shin, Ying Yuan, Louise C. Strong +2
Penetrance, which plays a key role in genetic research, is defined as the proportion of individuals with the genetic variants (i.e., {genotype}) that cause a particular trait and w…