2 papers
q-bio.QM2026
HyperEvoGen: Exploring deep phylogeny using non-Euclidean variational inference
Jason Lamanna, Erfan Mowlaei, Xinghua Shi +2
Homologous proteins evolve from a common ancestral sequence, constrained by intricate patterns of co-evolving residues. Accurate reconstruction of evolutionary histories remains a…
cond-mat.stat-mech2018
Is the free energy landscape informative about transition rates? Lessons from the kinetic Ising model
Daniel Sigg, Vincent A. Voelz, Vincenzo Carnevale
An oft-used concept in modeling macromolecules is the free energy landscape, obtained by coarse-graining a vast number of microstates into a low-dimensional mesh of mesostates. If…