62 citations · 62 across the 3 of their papers we have counts for
3 papers
Learning Deep Phylogeny Through Epistasis-Aware Geometry
Jason Lamanna, Erfan Mowlaei, Xinghua Shi +2
Epistasis shapes protein evolution because the effect of a substitution depends on its sequence background. Site-independent substitution models can recover phylogeny accurately, b…
Is the free energy landscape informative about transition rates? Lessons from the kinetic Ising model
Daniel Sigg, Vincent A. Voelz, Vincenzo Carnevale
An oft-used concept in modeling macromolecules is the free energy landscape, obtained by coarse-graining a vast number of microstates into a low-dimensional mesh of mesostates. If…
Convergent dynamics in the protease enzymatic superfamily
Vincenzo Carnevale, Simone Raugei, Cristian Micheletti +1
Proteases regulate various aspects of the life cycle in all organisms by cleaving specific peptide bonds. Their action is so central for biochemical processes that at least 2% of a…