3 papers
stat.AP2018
Crossing points in survival analysis sensitively depend on system conditions
Thomas McAndrew, Bjorn Redfors, Yiran Zhang +4
Crossing survival curves complicate how we interpret results from a clinical trial's primary endpoint. We find the function to determine a crossing point's location depends exponen…
stat.AP2018
How Cox models react to a study-specific confounder in a patient-level pooled dataset: Random-effects better cope with an imbalanced covariate across trials unless baseline hazards differ
Thomas McAndrew, Bjorn Redfors, Aaron Crowley +10
Combining patient-level data from clinical trials can connect rare phenomena with clinical endpoints, but statistical techniques applied to a single trial may become problematical…
stat.AP2018
Assimilated LVEF: A Bayesian technique combining human intuition with machine measurement for sharper estimates of left ventricular ejection fraction and stronger association with outcomes
Thomas McAndrew, Bjorn Redfors, Aaron Crowley +11
The cardiologist's main tool for measuring systolic heart failure is left ventricular ejection fraction (LVEF). Trained cardiologist's report both a visual and machine-guided measu…