3 papers
stat.AP2018
FastLORS: Joint Modeling for eQTL Mapping in R
Jacob Rhyne, Eric Chi, Jung-Ying Tzeng +1
Yang et al. (2013) introduced LORS, a method that jointly models the expression of genes, SNPs, and hidden factors for eQTL mapping. LORS solves a convex optimization problem and h…
stat.ME2018
Efficient Signal Inclusion With Genomic Applications
X. Jessie Jeng, Teng Zhang, Jung-Ying Tzeng
This paper addresses the challenge of efficiently capturing a high proportion of true signals for subsequent data analyses when sample sizes are relatively limited with respect to…
stat.AP2018
eQTL Mapping via Effective SNP Ranking and Screening
Jacob Rhyne, Jung-Ying Tzeng, Teng Zhang +1
Genome-wide eQTL mapping explores the relationship between gene expression values and DNA variants to understand genetic causes of human disease. Due to the large number of genes a…