activity
20122018
most citedCell responses only partially shape cell-to-cell variations in protein abundances in Escherichia coli chemotaxis

17 citations · 33 across the 5 of their papers we have counts for

collaborators

6 papers

stat.OT2018

Absolutely Zero Evidence

Veronica J. Vieland

Statistical analysis is often used to evaluate the evidence for or against scientific hypotheses, and various statistics (e.g., p-values, likelihood ratios, Bayes factors) are inte…

math.ST2015★ 2 cited

Statistical Evidence Measured on a Properly Calibrated Scale Across Nested and Non-nested Hypothesis Comparisons

V. J Vieland, S-C. Seok

Statistical modeling is often used to measure the strength of evidence for or against hypotheses on given data. We have previously proposed an information-dynamic framework in supp…

q-bio.CB2013★ 8 cited

In silico Modeling of Itk Activation Kinetics in Thymocytes Suggests Competing Positive and Negative IP4 Mediated Feedbacks Increase Robustness

Sayak Mukherjee, Stephanie Rigaud, Sang-Cheol Seok +7

The inositol-phosphate messenger inositol(1,3,4,5)tetrakisphosphate (IP4) is essential for thymocyte positive selection by regulating plasma-membrane association of the protein tyr…

q-bio.CB2013★ 17 cited

Cell responses only partially shape cell-to-cell variations in protein abundances in Escherichia coli chemotaxis

Sayak Mukherjee, Sang-Cheol Seok, Veronica J. Vieland +1

Cell-to-cell variations in protein abundance in clonal cell populations are ubiquitous in living systems. Since protein composition determines responses in individual cells, it sta…

q-bio.QM2013★ 6 cited

Data-driven quantification of robustness and sensitivity of cell signaling networks

Sayak Mukherjee, Sang-Cheol Seok, Veronica J. Vieland +1

Robustness and sensitivity of responses generated by cell signaling networks has been associated with survival and evolvability of organisms. However, existing methods analyzing ro…

math.ST2012

Measurement of statistical evidence on an absolute scale following thermodynamic principles

V. J. Vieland, J. Das, S. E. Hodge +1

Statistical analysis is used throughout biomedical research and elsewhere to assess strength of evidence. We have previously argued that typical outcome statistics (including p-val…