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stat.ME2025
Estimands for Randomized Discontinuation Designs in Oncology
Ayon Mukherjee, Oleksandr Sverdlov, Ngoc-Thuy Ha +1
Randomized discontinuation design (RDD) is an enrichment strategy commonly used to address limitations of traditional placebo-controlled trials, particularly the ethical concern of…
stat.ME2018
Lost in translation: On the impact of data coding on penalized regression with interactions
Johannes W R Martini, Francisco Rosales, Ngoc-Thuy Ha +3
Penalized regression approaches are standard tools in quantitative genetics. It is known that the fit of an \emph{ordinary least squares} (OLS) regression is independent of certain…