3 papers
physics.bio-ph2026
Confinement effects on protein stability in a freezing water environment
Yanis R. Espinosa, H. Ariel Alvarez, C. Manuel Carlevaro
Understanding how proteins behave at low temperatures remains a central challenge in biophysics, with direct implications for cold denaturation and cryopreservation. While cold den…
physics.bio-ph2025
Molecular Mechanisms Underlying the Effects of Urea and the Structural Dynamics of Bovine Serum Albumin
Y. Ricardo Espinosa, C. Manuel Carlevaro, C. Gastón Ferrara
The disruption of protein structures by denaturants like urea is well studied, though its molecular mechanisms remain unclear. Using Molecular Dynamics (MD) simulations, we investi…
physics.bio-ph2018
Behavior of H-FABP-fatty acid complex in a protein crystal simulation
Yanis R. Espinosa, H. Ariel Alvarez, Eduardo I. Howard +1
Crystallographic data comes from a space-time average over all the unit cells within the crystal, so dynamic phenomena do not contribute significantly to the diffraction data. Many…