12 citations · 32 across the 5 of their papers we have counts for
5 papers
Three dimensional simulations of embolic stroke: clinical comparisons and an equation for sizing emboli from imaging
James P. Hague, Jonathan Keelan, Lucy Beishon +3
There is a need to develop Monte Carlo simulations of stroke to run in-silico trials to replace animal models, explore clinical scenarios to develop hypotheses for clinical studies…
Development of a globally optimised model of the cerebral arteries
Jonathan Keelan, Emma M. L. Chung, James P. Hague
The cerebral arteries are difficult to reproduce from first principles, featuring interwoven territories, and intricate layers of grey and white matter with differing metabolic dem…
Simulated annealing approach to vascular structure with application to the coronary arteries
Jonathan Keelan, Emma M. L. Chung, James P. Hague
Does the complex processes of angiogenesis during organism development ultimately lead to a near optimal coronary vasculature in the organs of adult mammals? We examine this hypoth…
Modelling of impaired cerebral blood flow due to gaseous emboli
J. P. Hague, C. Banahan, E. M. L. Chung
Bubbles introduced to the arterial circulation during invasive medical procedures can have devastating consequences for brain function but their effects are currently difficult to…
Statistical physics of cerebral embolization leading to stroke
J. P. Hague, E. M. L. Chung
We discuss the physics of embolic stroke using a minimal model of emboli moving through the cerebral arteries. Our model of the blood flow network consists of a bifurcating tree, i…