4 papers
Continuum modeling of fluidic and elastic flow during growth-driven wound closure in partial-EMT cell monolayers
Chaozhen Wei, Han Jiang, Yifan Gu +5
Large-scale circular gap closure occurs over a time scale on which cell growth and proliferation become important. Growth is the main driver of the closing process, while cell dyna…
A phase-field model for viscoelastic compressible tumor growth
Luise Zieger, Min Wu, Chaozhen Wei +2
It is well known that growing tumors generate and respond to stress in their local microenvironment. Tissue re-arrangements can relax these mechanical stresses and make the tissue…
Inferring Exocytosis Profiles from Cell Shapes Using a Dual-Configuration Model of Walled Cell Tip Growth
Kamryn Spinelli, Chaozhen Wei, Luis Vidali +1
Tip growth in filamentous cells, such as root hairs, moss protonemata, and fungal hyphae, depends on coordinated cell wall extension driven by turgor pressure, wall mechanics, and…
Chemomechanical regulation of growing tissues from a thermodynamically-consistent framework and its application to tumor spheroid growth
Nonthakorn Olaranont, Chaozhen Wei, John Lowengrub +1
It is widely recognized that reciprocal interactions between cells and their microenvironment, via mechanical forces and biochemical signaling pathways, regulate cell behaviors dur…