15 citations · 33 across the 8 of their papers we have counts for
8 papers
Flags, Landscapes and Signaling: Contact-mediated inter-cellular interactions enable plasticity in fate determination driven by positional information
Chandrashekar Kuyyamudi, Shakti N. Menon, Sitabhra Sinha
Multicellular organisms exhibit a high degree of structural organization with specific cell types always occurring in characteristic locations. The conventional framework for descr…
Contact-mediated signaling enables disorder-driven transitions in cellular assemblies
Chandrashekar Kuyyamudi, Shakti N. Menon, Sitabhra Sinha
We show that when cells communicate by contact-mediated interactions, heterogeneity in cell shapes and sizes leads to qualitatively distinct collective behavior in the tissue. For…
Precision of morphogen-driven tissue patterning during development is enhanced through contact-mediated cellular interactions
Chandrashekar Kuyyamudi, Shakti N. Menon, Sitabhra Sinha
Embryonic development involves pattern formation characterized by the emergence of spatially localized domains characterized by distinct cell fates resulting from differential gene…
Disorder in cellular packing can alter proliferation dynamics to regulate growth
Chandrashekar Kuyyamudi, Shakti N. Menon, Fernando Casares +1
Controlling growth via cell division is crucial in the development of higher organisms, and yet the mechanisms through which this is achieved, e.g., in epithelial tissue, is not ye…
Contact-mediated cellular communication supplements positional information to regulate spatial patterning during development
Chandrashekar Kuyyamudi, Shakti N. Menon, Sitabhra Sinha
Development in multi-cellular organisms is marked by a high degree of spatial organization of the cells attaining distinct fates in the embryo. We show that receptor-ligand interac…
Morphogen-regulated contact-mediated signaling between cells can drive the transitions underlying body segmentation in vertebrates
Chandrashekar Kuyyamudi, Shakti N. Menon, Sitabhra Sinha
We propose a unified mechanism that reproduces the sequence of dynamical transitions observed during somitogenesis, the process of body segmentation during embryonic development, t…
Emergence of frustration signals systemic risk
Chandrashekar Kuyyamudi, Anindya S. Chakrabarti, Sitabhra Sinha
We show that the emergence of systemic risk in complex systems can be understood from the evolution of functional networks representing interactions inferred from fluctuation corre…
Modularity promotes epidemic recurrence
T. Jesan, Chandrashekar Kuyyamudi, Sitabhra Sinha
The long-term evolution of epidemic processes depends crucially on the structure of contact networks. As empirical evidence indicates that human populations exhibit strong communit…