110 citations · 224 across the 5 of their papers we have counts for
5 papers
Entropic contribution to phenotype fitness
Pablo Catalán, Juan Antonio García-Martín, Jacobo Aguirre +2
All possible phenotypes are not equally accessible to evolving populations. In fact, only phenotypes of large size, i.e. those resulting from many different genotypes, are found in…
From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics
Susanna Manrubia, José A. Cuesta, Jacobo Aguirre +15
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is arguably the next major missing piece in a fully predictive theory of evolution. We refer to t…
Statistical theory of phenotype abundance distributions: a test through exact enumeration of genotype spaces
Juan Antonio García-Martín, Pablo Catalán, Susanna Manrubia +1
The evolutionary dynamics of molecular populations are strongly dependent on the structure of genotype spaces. The map between genotype and phenotype determines how easily genotype…
On the networked architecture of genotype spaces and its critical effects on molecular evolution
Jacobo Aguirre, Pablo Catalán, José A. Cuesta +1
Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inhe…
toyLIFE: a computational framework to study the multi-level organization of the genotype-phenotype map
Clemente F. Arias, Pablo Catalán, Susanna Manrubia +1
The genotype-phenotype map is an essential object in our understanding of organismal complexity and adaptive properties, determining at once genomic plasticity and those constraint…