887 citations · 1.1k across the 4 of their papers we have counts for
4 papers
Systematic conformation-to-phenotype mapping via limited deep-sequencing of proteins
Eugene Serebryany, Victor Y. Zhao, Kibum Park +4
Non-native conformations drive protein misfolding diseases, complicate bioengineering efforts, and fuel molecular evolution. No current experimental technique is well-suited for el…
Mass-spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation
Bogdan Budnik, Ezra Levy, Guillaume Harmange +1
Cellular heterogeneity is important to biological processes, including cancer and development. However, proteome heterogeneity is largely unexplored because of the limitations of e…
Quantifying homologous proteins and proteoforms
Dmitry Malioutov, Tianchi Chen, Jacob Jaffe +4
Many proteoforms - arising from alternative splicing, post-translational modifications (PTMs), or paralogous genes - have distinct biological functions, such as histone PTM proteof…
Differential stoichiometry among core ribosomal proteins
Nikolai Slavov, Sefan Semrau, Edoardo Airoldi +2
Understanding the regulation and structure of ribosomes is essential to understanding protein synthesis and its deregulation in disease. While ribosomes are believed to have a fixe…