activity
20182026
most citedCooperation of dual modes of cell motility promotes epithelial stress relaxation to accelerate wound healing

70 citations · 114 across the 11 of their papers we have counts for

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Showing physics.bio-phShow all

7 papers · 1 filter

physics.bio-ph2026

Cell proliferation maintains cell area polydispersity in the growing fruit fly wing epithelium

Michael F. Staddon, Natalie A. Dye, Marko Popović +1

Developing epithelial tissues coordinate cell proliferation and mechanical forces to achieve proper size and shape. As epithelial cells tightly adhere together to form the confluen…

physics.bio-ph2025

Phyllotaxis in a Keller-Segel model

Michael F. Staddon

Plants often exhibit regular arrangements of seeds or leaves, known as phyllotaxis, and can famously exhibit Fibonacci spirals, as in sunflower heads or on pine cones. While there…

physics.bio-ph2024

Curved edges in the vertex model increase tissue fluidity

Michael F. Staddon, Carl D. Modes

The Vertex Model for epithelia models the apical surface of the tissue by a tiling, with polygons representing cells and edges representing cell-cell junctions. The mechanics are d…

physics.bio-ph2023★ 1 cited

How the zebra got its stripes: Curvature-dependent diffusion orients Turing patterns on 3D surfaces

Michael F. Staddon

Many animals have patterned fur, feathers, or scales, such as the stripes of a zebra. Turing models, or reaction-diffusion systems, are a class of mathematical models of interactin…

physics.bio-ph2022

Interplay between substrate rigidity and tissue fluidity regulates cell monolayer spreading

Michael F. Staddon, Michael P. Murrell, Shiladitya Banerjee

Coordinated and cooperative motion of cells is essential for embryonic development, tissue morphogenesis, wound healing and cancer invasion. A predictive understanding of the emerg…

physics.bio-ph2018★ 70 cited

Cooperation of dual modes of cell motility promotes epithelial stress relaxation to accelerate wound healing

Michael F. Staddon, Dapeng Bi, A. Pasha Tabatabai +3

Collective cell migration in cohesive units is vital for tissue morphogenesis, wound repair, and immune response. While the fundamental driving forces for collective cell motion st…

physics.bio-ph2018★ 1 cited

Epithelial Wound Healing Coordinates Distinct Actin Network Architectures to Conserve Mechanical Work and Balance Power

Visar Ajeti, A. Pasha Tabatabai, Andrew J. Fleszar +8

How cells with diverse morphologies and cytoskeletal architectures modulate their mechanical behaviors to drive robust collective motion within tissues is poorly understood. During…