5 papers
Multiscale Network Model for Fibrin Fibers and Fibrin Clot with Protofibril Binding Mechanics
Sumith Yesudasan, Rodney D Averett
The multiscale behavior of the individual fibrin fibers and fibrin clots is modeled by coupling atomistic simulation data and microscopic experimental data. We propose a protofibri…
Recent Advances in Computational Modeling of Thrombosis
Sumith Yesudasan, Rodney D. Averett
The study of thrombosis is crucial to understand and develop new therapies for diseases like deep vein thrombosis, diabetes related strokes, pulmonary embolism etc. The last two de…
Coarse Grain Molecular Dynamics Simulation of Fibrin Polymerization
Sumith Yesudasan, Rodney D. Averett
Studies suggests that patients with deep vein thrombosis and diabetes often have hy-per coagulable blood plasma leading to higher chances of forming thromboembolisms by the rupture…
Molecular Dynamics Simulations Indicate that Deoxyhemoglobin, Oxyhemoglobin, Carboxyhemoglobin, and Glycated Hemoglobin under Compression and Shear Exhibit an Anisotropic Mechanical Behavior
Sumith Yesudasan, Xianqiao Wang, Rodney D. Averett
We developed a new mechanical model for determining the compression and shear mechanical behavior of four different hemoglobin structures. Previous studies on hemoglobin structures…
Electromagnetically Induced Distortion of a Fibrin Matrix with Embedded Microparticles
Tyler Scogin, Sumith Yesudasan, Mitchell L. R. Walker +1
Blood clots occur in the human body when they are required to prevent bleeding. In pathological states such as diabetes and sickle cell disease, blood clots can also form undesirab…