Clumped Nuclei Segmentation with Adjacent Point Match and Local Shape based Intensity Analysis for Overlapped Nuclei in Fluorescence In-Situ Hybridization Images

Xiaoyuan Guo, Hanyi Yu, Blair Rossetti +3

Highly clumped nuclei clusters captured in fluorescence in situ hybridization microscopy images are common histology entities under investigations in a wide spectrum of tissue-rela…