2 papers
q-bio.GN2018
Pharmacogenomics in the Age of GWAS, Omics Atlases, and PheWAS
Ari Allyn-Feuer, Gerald A. Higgins, Brian D. Athey
The search for causative pharmacogenomic loci is being transformed by integrative omics pipelines, but their outputs have only begun being applied to test design. We assess the dir…
q-bio.QM2018
Deep Learning in Pharmacogenomics: From Gene Regulation to Patient Stratification
Alexandr A. Kalinin, Gerald A. Higgins, Narathip Reamaroon +5
This Perspective provides examples of current and future applications of deep learning in pharmacogenomics, including: (1) identification of novel regulatory variants located in no…